肥満細胞性白血病に対する化学療法開始直後に難治性アナフィラキシーショックを来した1例(A case of refractory anaphylactic shock immediately following initiation of chemotherapy for mast cell leukemia)

Key Points

• This report focuses on a case of recurrent anaphylactic shock following the initiation of chemotherapy for mast cell leukemia.
• Detailed case study of a 49-year-old female with mast cell leukemia who experienced anaphylactic shock after chemotherapy initiation.
• Interventions included fluid resuscitation, intramuscular adrenaline injection, steroids, and histamine H1 receptor antagonists.
• Continuous intravenous adrenaline was administered for stabilization after minimal response to standard treatments.
• The patient developed significant hypotension, facial flushing, and oxygen desaturation post-chemotherapy.
• Initial treatment led to temporary shock resolution, but recurrent episodes of anaphylactic shock occurred every few hours.
• With sustained adrenaline administration, the patient's condition stabilized without further complications.