Acute exhaustive swim exercise in mice caused a disproportionate negative impact on the right ventricle, reflecting a ~2-fold greater hemodynamic RV load versus the left ventricle.
Acute exhaustive exercise differentially impacts the right ventricle (RV) versus left ventricle (LV), yet the underlying hemodynamic basis remains unclear. Using pressure-volume analyses and pressure-telemetry implantation in mice, we confirmed a marked disproportionate and persistent negative impact of exhaustive exercise on the RV. These differences in responses of the ventricles to exhaustive exercise are of clinical relevance, reflecting ∼2-fold greater hemodynamic RV loads versus LVs arising from massive (∼45 mmHg) increases in LV end-diastolic pressures at exhaustion.
Lakin et al. (Fri,) reported a other. Acute exhaustive swim exercise was evaluated on Hemodynamic impact on the right ventricle versus left ventricle. Acute exhaustive swim exercise in mice caused a disproportionate negative impact on the right ventricle, reflecting a ~2-fold greater hemodynamic RV load versus the left ventricle.
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