Echocardiographically-derived pulmonary arterial elastance strongly correlated with invasive catheterization (r=0.897, p<0.001) with a mean bias of -0.06 mm Hg/mL.
Cross-Sectional (n=31)
Does echocardiographically-derived pulmonary arterial elastance accurately estimate right ventricular afterload compared to right heart catheterization in patients with systolic heart failure?
Doppler echocardiography provides an accurate and reliable non-invasive estimation of pulmonary arterial elastance compared to right heart catheterization in patients with systolic heart failure.
Mean Difference: -0.06 (95% CI -0.36–0.48)
Absolute Event Rate: 0.67% vs 0.73%
p-value: p=<0.001
OBJECTIVE: A reliable and easy-to-perform method for measuring right ventricular (RV) afterload is desirable when scheduling patients with systolic heart failure to undergo heart transplantation. The present study aimed to investigate the accuracy of echocardiographically-derived pulmonary arterial elastance as a measurement of pulmonary vascular resistance by comparing it with invasive measures. METHODS: Thirty-one patients with moderate to severe systolic heart failure, including 22 (71%) male patients, with a mean age of 41.16 ± 15.9 years were enrolled in the study. Right heart catheterization and comprehensive echocardiography during the first hour after completion of cardiac catheterization were performed in all the patients. The pulmonary artery elastance was estimated using the ratio of end-systolic pressure (Pes) over the stroke volume (SV) by both cardiac catheterization Ea (PV)-C and echocardiography Ea (PV)-E. RESULTS: The mean Ea (PV)-C and Ea (PV)-E were estimated to be 0.73 ± 0.49 mm Hg/mL and 0.67 ± 0.44 mm Hg/mL, respectively. There was a significant relation between Ea (PV)-E and Ea (PV)-C (r=0.897, p<0.001). Agreement between echocardiography and catheterization methods for estimating Ea (PV), investigated by the Bland-Altman method, showed a mean bias of -0.06, with 95% limits of agreement from -0.36 mm Hg/mL to 0.48 mm Hg/mL. CONCLUSION: Doppler echocardiography is an easy, non-invasive, and inexpensive method for measuring pulmonary arterial elastance, which provides accurate and reliable estimation of RV afterload in patients with systolic heart failure.
Taghavi et al. (Wed,) conducted a cross-sectional in Moderate to severe systolic heart failure (n=31). Echocardiographically-derived pulmonary arterial elastance vs. Invasive measurement by right heart catheterization was evaluated on Agreement between echocardiography and catheterization methods for estimating pulmonary arterial elastance (mean bias -0.06, 95% CI -0.36 to 0.48, p=<0.001). Echocardiographically-derived pulmonary arterial elastance strongly correlated with invasive catheterization (r=0.897, p<0.001) with a mean bias of -0.06 mm Hg/mL.
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