In septuagenarians undergoing emergency laparotomy, all-cause mortality was 35.3% at 19 months, and higher preoperative clinical frailty scale scores significantly predicted mortality (p<0.0001).
Cohort (n=153)
No
What is the effect of clinical frailty on mortality and quality of life in septuagenarian patients after emergency laparotomy?
In septuagenarian patients undergoing emergency laparotomy, preoperative frailty is a significant predictor of mortality and is associated with long-term deterioration in physical and social functioning.
p-value: p=<0.0001
Introduction The UK has an ageing population with an increased prevalence of frailty in the over 70s. Emergency laparotomy for acute intra-abdominal pathology is increasingly offered to this population. This can challenge decision making and information given to patients should not only be based on mortality outcomes but on relative expected quality of life and change to frailty syndromes. Materials and methods This was a single site National Emergency Laparotomy Audit (NELA)-based retrospective cohort audit for consecutive cases in the septuagenarian population assessing mortality, length of stay outcome and subjective postoperative functioning. Follow-up was conducted between one and two years postoperatively to determine this. Results Some 153 patients were identified throughout the single site NELA database. Median age was 79 years with a ratio of 1.7 men to women. Median rate of all-cause mortality was 35.3% at the median follow-up of 19 months. Median time from admission to death was 120 days. Of those who had died by the time of follow-up, significant preoperative indicators included clinical frailty scale (p < 0.0001), preoperative P-POSSUM (mortality). At follow-up, 35% responded to a quality of life follow-up. This revealed a decline in mid-term physical functioning, lower energy, higher fatigue and reduction in social functioning. There was also an increase in pre- and postoperative clinical frailty scale score. Conclusion In the septuagenarian-plus population it is important to consider not only risk stratification with mortality scoring (P-POSSUM or NELA-adjusted risk), but to take into account frailty. Postoperative rehabilitation and careful recovery is paramount. Where possible, during the counselling and consent for emergency laparotomy, significant postoperative long-term deterioration in physical, emotional and social function should be considered.
Alder et al. (Mon,) conducted a cohort in Acute intra-abdominal pathology requiring emergency laparotomy (n=153). Clinical frailty was evaluated on All-cause mortality (p=<0.0001). In septuagenarians undergoing emergency laparotomy, all-cause mortality was 35.3% at 19 months, and higher preoperative clinical frailty scale scores significantly predicted mortality (p<0.0001).