Empirically based assessment and taxonomy: Applications to clinical research.

The empirically based paradigm uses standardized procedures to assess problems reported by different informants. Multivariate analyses are used to derive taxonomic constructs comprising syndromes that are robust across samples and assessment procedures. The taxonomic constructs are operationally defined via scales that are normed in relation to participants' characteristics and the sources of data. New cases can be evaluated via the same assessment procedures that are used to derive and operationalize the constructs. Spanning from age 2 to 27, applications of the paradigm were illustrated with cross-cultural, longitudinal, accelerated longitudinal, treatment, and diagnostic studies. The empirically based approach provides productive alternatives to the agendas for research and services implied by the Diagnostic and Statistical Manual of Mental Disorders, especially in managed care contexts.