A 30-minute preoperative physiotherapy session halved the incidence of postoperative pulmonary complications compared to an information booklet (HR 0.48; 95% CI 0.30-0.75; P=0.001).
RCT (n=441)
Double-blind
concealed allocation
Yes
Does a single preoperative physiotherapy session reduce postoperative pulmonary complications in adults undergoing elective major open upper abdominal surgery?
A single 30-minute preoperative physiotherapy session significantly reduces the incidence of postoperative pulmonary complications after major upper abdominal surgery.
Hazard Ratio: 0.48 (95% CI 0.3–0.75)
Absolute Risk Reduction: 15%
Number Needed to Treat: 7
p-value: p=0.001
OBJECTIVE: To assess the efficacy of a single preoperative physiotherapy session to reduce postoperative pulmonary complications (PPCs) after upper abdominal surgery. DESIGN: Prospective, pragmatic, multicentre, patient and assessor blinded, parallel group, randomised placebo controlled superiority trial. SETTING: Multidisciplinary preadmission clinics at three tertiary public hospitals in Australia and New Zealand. PARTICIPANTS: 441 adults aged 18 years or older who were within six weeks of elective major open upper abdominal surgery were randomly assigned through concealed allocation to receive either an information booklet (n=219; control) or preoperative physiotherapy (n=222; intervention) and followed for 12 months. 432 completed the trial. INTERVENTIONS: Preoperatively, participants received an information booklet (control) or an additional 30 minute physiotherapy education and breathing exercise training session (intervention). Education focused on PPCs and their prevention through early ambulation and self directed breathing exercises to be initiated immediately on regaining consciousness after surgery. Postoperatively, all participants received standardised early ambulation, and no additional respiratory physiotherapy was provided. MAIN OUTCOME MEASURES: The primary outcome was a PPC within 14 postoperative hospital days assessed daily using the Melbourne group score. Secondary outcomes were hospital acquired pneumonia, length of hospital stay, utilisation of intensive care unit services, and hospital costs. Patient reported health related quality of life, physical function, and post-discharge complications were measured at six weeks, and all cause mortality was measured to 12 months. RESULTS: The incidence of PPCs within 14 postoperative hospital days, including hospital acquired pneumonia, was halved (adjusted hazard ratio 0.48, 95% confidence interval 0.30 to 0.75, P=0.001) in the intervention group compared with the control group, with an absolute risk reduction of 15% (95% confidence interval 7% to 22%) and a number needed to treat of 7 (95% confidence interval 5 to 14). No significant differences in other secondary outcomes were detected. CONCLUSION: In a general population of patients listed for elective upper abdominal surgery, a 30 minute preoperative physiotherapy session provided within existing hospital multidisciplinary preadmission clinics halves the incidence of PPCs and specifically hospital acquired pneumonia. Further research is required to investigate benefits to mortality and length of stay. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry ANZCTR 12613000664741.
Boden et al. (Wed,) conducted a rct in elective major open upper abdominal surgery (n=441). Preoperative physiotherapy vs. Information booklet was evaluated on Postoperative pulmonary complication (PPC) within 14 postoperative hospital days (HR 0.48, 95% CI 0.30 to 0.75, p=0.001). A 30-minute preoperative physiotherapy session halved the incidence of postoperative pulmonary complications compared to an information booklet (HR 0.48; 95% CI 0.30-0.75; P=0.001).