Drug Interactions Analysis and Management 2009

Drug Interactions Analysis and Management 2009 ISBN: 978-1-57439-311-8. Copyright: 2009. Edition: 1st. Editors: Philip D. Hansten, PharmD; John R. Horn, PharmD. Specialties: Pharmacy, General Medicine, Advanced Practice, Pharmacology. Publisher: Wolters Kluwer Health. List Price: 99. 95 DESCRIPTION: This reference book provides organized, concise, and practical drug interaction monographs (i. e. , prescription, nonprescription, and herbal products) that can easily be applied in clinical practice. For each method covered, the book provides step-by-step protocols, illustrated by typical research applications. PURPOSE: To provide information that can be applied in clinical practice to avoid the adverse outcomes of drug interactions. AUDIENCE: The book can be used by any healthcare professional who prescribes, dispenses, or administers medications including physicians, pharmacists, and nurses. FEATURES: The majority of the book is made up of drug interaction monographs, organized alphabetically by generic name. Each provides a summary of the drug interaction, the risk factors that increase the likelihood of the interaction, and the proposed mechanism. The helpful introductory chapter describes the different mechanisms and the time course of drug interactions, which is important for clinicians to monitor for a potential effect. The various mechanisms for pharmacokinetic interactions also are outlined, with examples of each type. Some examples, such as common drug inducers and inhibitors, are organized in table format, allowing easy reference. Newer concepts, such as grapefruit juice interactions and P-glycoprotein, also are described. ASSESSMENT: This book succeeds in providing accurate, updated, and practical information that healthcare professionals can easily access. The book differentiates itself from others on drug interactions because its classification system focuses on managing the drug interaction. These recommendations are supported by evidence, with references that allow readers to further explore published data on the potential interaction. The text is written by authorities in the field, at an appropriate level for the intended audience. The information can easily be applied to patient care because it is concise, easily referenced, and practical. The index also allows readers to quickly access information and provides a risk rating for each interaction. RATING: ★★★★★ Reviewed by: Melissa Ranieri, PharmD (Temple University School of Pharmacy, Philadelphia, PA)