What question did this study set out to answer?

This research aims to develop and evaluate meso-aryl free-base porphyrins for selective creatinine detection in various media.

June 4, 2026Materials Advances0 citationsOpen Access

Hydrogen-Bonding Mediated Supramolecular Assembly of Fluorescent Meso-Aryl Porphyrins for Creatinine Monitoring in Biological Samples

KSKarisma SharmaUniversity of London APAnimesh PalKyushu University SJSatadru JhaUniversity of Padua

Key Points

This research aims to develop and evaluate meso-aryl free-base porphyrins for selective creatinine detection in various media.
Design and synthesize two fluorescent meso-aryl porphyrins.
Conduct mechanistic evaluations for creatinine detection.
Test in aqueous and biological samples.
Both probes exhibited selective detection capabilities for creatinine.
Demonstrated effective fluorescence response in biological media.
Provided quantitative measurements for creatinine concentration.

Abstract

Herein, we report the design, synthesis, and mechanistic evaluation of two meso-aryl free-base porphyrins for selective detection of creatinine in aqueous as well as in biological media. Probe 1, with...

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