NMM-promoted decarboxylative C(sp³)–C(sp³) coupling of coumarin-3-carboxylic acids and indolin-3-ones

Key Points

• This study aims to develop a new method for constructing C(sp³)–C(sp³) bonds using a tandem reaction of specific compounds.
• Utilized a tandem reaction involving coumarin-3-carboxylic acids and indolin-3-ones.
• Employed Michael addition followed by decarboxylation at room temperature.
• Focus on a straightforward synthesis without complex procedures.
• Successfully formed C(sp³)–C(sp³) bonds under mild conditions.
• Achieved high yields of desired products using the tandem reaction strategy.
• Showed the reaction effectiveness in various substrate combinations.