This article systematically analyzes modern laboratory diagnostic methods for herpes virus infection. Diseases caused by the herpes virus — including labial, genital, ophthalmic herpes, and neuroinfections — are widespread worldwide, making timely and accurate diagnosis highly important. The article comprehensively describes virological methods (virus isolation in cell culture), cytological examination, immunological methods (immunofluorescence, enzyme-linked immunosorbent assay, immunoblot), and molecular genetic methods (polymerase chain reaction, real-time polymerase chain reaction, genotyping, and antiviral resistance genotyping). The sensitivity, specificity, advantages, and limitations of each method are presented based on scientific sources.
Abdurahmonova et al. (Tue,) studied this question.
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