CMR-TT established normal values for left and right atrial strains in healthy adults, revealing that right atrial strains are generally larger than left atrial strains and decrease with age.
Cross-Sectional (n=150)
No
What are the age- and gender-specific normal values for left and right atrial strains assessed by cardiovascular magnetic resonance based tissue tracking in healthy adults?
CMR-TT is a feasible and reproducible technique for quantifying bi-atrial strains, demonstrating that atrial reservoir and conduit functions decrease with age and differ by gender, highlighting the need for population-specific normal values.
Background: Left and right atrium (LA and RA) exert an essential and dynamic role in ventricular filling and hence affect heart performance. Strain quantification has been reported as a novel parameter to assess function. However, the assessment of bi-atrial strains with cardiovascular magnetic resonance (CMR) based techniques is still limited and gender- and age-specific normal values in a healthy population are missing. Methods: One hundred and fifty healthy volunteers (49.8 ± 17.3 years, 75 males) undergoing 1.5 Tesla CMR examination were retrospectively and consecutively recruited. LA and RA free wall (RAFW) radial and longitudinal strains (RS and LS) associated with atrial reservoir, conduit and booster pump functions were evaluated with CMR based tissue tracking (CMR-TT) technique. Results: The reservoir, conduit and pump LS resulted as 30.7 ± 10.2%, 19.5 ± 8.2%, 10.9 ± 3.7% for LA, and 52.2 ± 17.6%, 33.3 ± 14.2%, 19.1 ± 8.5% for RAFW, respectively. The amplitude of RA strains was significantly larger than that of LA strains, except for conduit RS. With the increase of age, the decrement of majority of reservoir and conduit strains were observed, while pump strains remained unaffected. Females presented with significantly larger RAFW strains compared with males, especially in the elderly. In addition to the positive correlation between atrial strains and emptying fraction, the negative correlation between atrial strains and volume index was also confirmed. Intra-observer reproducibility of LA strains was superior to RAFW strains (coefficient of variation: 10.12–17.04% vs. 10.80–27.36%, respectively), and the measurement of reservoir and conduit strains was more reproducible in comparison with pump strain. Conclusion: CMR-TT is a feasible and reproducible technique to quantify LA and RA strains and determine atrial phasic functions. The existence of age- and gender-related difference of strains suggests the necessity to establish specific normal values for individual populations.
Qu et al. (Thu,) conducted a cross-sectional in Healthy volunteers (n=150). Cardiovascular Magnetic Resonance Based Tissue Tracking (CMR-TT) was evaluated on Normal values of LA and RA reservoir, conduit, and pump longitudinal strains. CMR-TT established normal values for left and right atrial strains in healthy adults, revealing that right atrial strains are generally larger than left atrial strains and decrease with age.
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