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June 5, 20260 citationsOpen Access

A Comprehensive Review on the Therapeutic Role of Corticosteroids in Dermatological Disease Management

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DUDr. S. Aravinth Vijay Jesuraj2 Ms. Malavika P U*1

Key Points

  • This review aims to detail the therapeutic role of corticosteroids in managing dermatological diseases, addressing both efficacy and safety.
  • Comprehensive overview of corticosteroids' mechanisms of action and clinical applications.
  • Discussion of appropriate prescribing practices and strategies to enhance patient adherence.
  • Analysis of safety concerns related to corticosteroid use, including potential adverse effects.
  • Corticosteroids demonstrate substantial anti-inflammatory effects, beneficial in managing diverse skin conditions.
  • Proper selection of corticosteroid potency and therapy duration can enhance treatment outcomes and minimize adverse effects.
  • Highlighting key safety concerns related to prolonged use underscores the need for careful management in clinical practice.

Abstract

Skin diseases represent a significant global health burden, affecting millions of individuals and contributing substantially to morbidity and reduced quality of life. Common dermatological conditions such as psoriasis, atopic dermatitis, seborrheic dermatitis, contact dermatitis, acne vulgaris, and vitiligo are largely driven by inflammatory and immune-mediated mechanisms. Among available therapeutic options, corticosteroids remain a cornerstone in dermatological practice due to their potent anti-inflammatory and immunosuppressive properties. This review provides a comprehensive overview of the role of corticosteroids in the management of various skin disorders, focusing on their mechanisms of action, clinical applications, pharmacokinetics, pharmacodynamics, and classification. It also highlights appropriate prescribing practices, including selection of potency, duration of therapy, and methods to enhance patient adherence while minimizing adverse effects. Special emphasis is placed on safety concerns associated with prolonged or inappropriate use, such as local skin changes and systemic complications. This review aims to provide a comprehensive overview of the therapeutic effectiveness, clinical applications, safety considerations in corticosteroid therapy for dermatological conditions.

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Dr. S. Aravinth Vijay Jesuraj2 Ms. Malavika P U*1 (2026) studied this question.

synapsesocial.com/papers/6a226835763171746d546c77https://doi.org/10.5281/zenodo.20525019
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Steroid-induced dermatitis: features of pathogenesis and treatment challenges2026
  2. 2Prescribing patterns and analyzing the usage of corticosteroid therapy at tertiary care hospital2024
  3. 3Exploring Newer Topical Therapies for Inflammatory Skin Diseases: A Guide for Rheumatologists2024
  4. 4Review on Knowledge, Attitude and Practice among Patients with Topical Steroid-Dependent Face2026
  5. 5Corticosteroid Phobia in Patients with Atopic Dermatitis: A Narrative Review2026