(876) Geometric Characteristics of the Penis Associated with Peyronie’s Disease: A Cross-Sectional Study

Abstract Introduction Peyronie’s disease affects approximately 8% of men and is associated with morphometric changes in the penis, such as shortening and deformities that impair sexual function. However, penile morphometric parameters can vary substantially across different populations, influenced by ethnic, geographic, and methodological factors used in measurements. Objective To investigate penile geometric characteristics in patients diagnosed with Peyronie’s disease. Methods This was a single-center, cross-sectional study involving men who sought private andrology care between January and October 2025. The variables analyzed included presence of penile curvature (yes/no), direction of curvature (dorsal, ventral, lateral, dorsolateral, ventrolateral), degree of curvature (in degrees), plaque location (proximal, middle, distal), indentation (yes/no), distal hypotrophy (yes/no), penile length (cm), and penile circumference (cm). All data were collected during pharmacologically induced penile Doppler ultrasonography. Data analysis was performed using RStudio software. Results A total of 123 men diagnosed with Peyronie’s disease were included, with a mean age of 56 ± 11.9 years. A high prevalence of penile deformity was observed, present in 97.6% of cases. The most common curvature direction was dorsal (54.7%), followed by dorsal+lateral (20.0%), lateral (17.9%), ventral+lateral (5.3%), and ventral (2.1%). Plaques were most frequently located in the middle region (64.9%), followed by distal (18.6%) and proximal (16.5%) regions. The mean curvature angle was 44.36° ± 23.19. Other frequent geometric alterations included indentation (36.7%) and distal hypotrophy (43.1%). Regarding dimensional measurements, the mean stretched penile length was 13.80 ± 1.76 cm, and the mean penile circumference was 11.96 ± 1.72 cm. Conclusions In this sample of men with Peyronie’s disease, penile geometric alterations were prevalent, with dorsal curvature, middle plaque location, indentation, and distal hypotrophy being the most common findings. Disclosure No