1571-P: The Diabetes Tune-Up Group: Treating Diabetes Distress in Black and African American Women with T2D

Introduction and Objective: Black and African American (BAA) women have a high burden of type 2 diabetes (T2D) and diabetes distress (DD). We tested the efficacy of a culturally-tailored Diabetes Tune-Up Group intervention delivered in-person or by synchronous video call (VC) to BAA women with DD and T2D. Methods: 63 BAA women were enrolled in a waitlist-controlled repeated measures trial. Data collected at enrollment (T1), baseline (T2), post-intervention (T3) and 3-month follow-up (T4) included: demographics, Diabetes Distress Scale-17 (DDS-17), depressive symptoms (PHQ-9), diabetes self-efficacy (CIDS), quality of life (SF-12) and A1c. 50 women (79% retention rate) completed measures (reported below) at all time points. Results: At enrollment, participants’ mean (M) age was 62. 6 years (S. D. = 11. 3), 98% Black/African American, 71% single, 33. 4 (S. D. = 6. 9) mean BMI with a median annual household income of 21, 000- 40, 000. Mean A1c was 7. 86% (S. D. = 1. 35%). Treatment regimen: oral hypoglycemic agents (50%), combination therapy (35. 2%), and diet and exercise alone (6. 2%). A Freestyle Libre 2. 0 or 3. 0 CGM was provided at each assessment timepoint and throughout the intervention. As predicted, no changes were observed from T1 to T2 (waitlist period) in A1c, total DDS-17 or PHQ-9 (all p’s = N. S. ). Across the whole sample (in person and VC), significant changes from T2 to T4 (pre-intervention - 3-month follow-up) were observed in total DDS-17 (M = 2. 54 (S. D. = 0. 81) to M = 1. 97 (S. D = 0. 85), t = -4. 94, p. 001), PHQ-9 (M = 5. 56 (S. D. = 4. 09) to M = 3. 23 (S. D. = 3. 44), t = -5. 31, p. 001), CIDS (t = 4. 43, p. 001) and PCS-12 (t = 4. 46, p. 001). A1c showed a non-significant improvement. Primary and secondary outcomes did not differ by treatment modality (in-person vs. VC) after accounting for covariates (age, income, duration of diabetes and changes in medications; all p’s=NS). Conclusion: The Diabetes Tune Up Group is an efficacious intervention to treat diabetes distress for BAA women with T2D delivered in-person or by VC. Findings support potential scalability of VC delivery. Disclosure M. de Groot: None. K. Pinner: None. R. Klingensmith: None. B. A. Myers: None. L. E. Baker: None. B. Merchant: None. K. Haynes: None. J. S. Alwine: Stock/Shareholder; Current; Arrowhead Pharmaceuticals, Inc. Z. Yang: None. G. Bakoyannis: None. Funding American Diabetes Association (4-22-ICTSHD-44)