Oncological Safety of Autologous Fat Grafting Following Breast Reconstructive and Cosmetic Surgery: A Systematic Review

Key Points

• To evaluate clinical evidence on the oncological safety of autologous fat grafting in breast surgery, focusing on cancer recurrence and risks of new tumors.
• Conducted a systematic review of existing literature on autologous fat grafting and its oncological implications.
• Analyzed data regarding cancer recurrence and new primary tumors in patients undergoing breast reconstructive and cosmetic surgery using AFG.
• Evaluated studies that specifically address the safety concerns related to adipose-derived stem cells.
• Some studies indicate no significant increase in cancer recurrence rates following AFG.
• Other studies highlight potential risks of new primary tumors, warranting further investigation into long-term safety.
• The evidence is mixed, emphasizing the need for ongoing monitoring and research regarding AFG and oncological outcomes.