Cardiovascular disease, developing either before or after a cancer diagnosis, is associated with an increased risk of cancer and worse patient outcomes.
The field of cardio-oncology has emerged in response to the increased risk of cardiovascular disease (CVD) in patients with cancer. However, recent studies suggest a more complicated CVD-cancer relationship, wherein development of CVD, either prior to or following a cancer diagnosis, can also lead to increased risk of cancer and worse outcomes for patients. In this review, we describe the current evidence base, across epidemiological as well as preclinical studies, which supports the emerging concept of 'reverse-cardio oncology', or CVD-induced acceleration of cancer pathogenesis.
Koelwyn et al. (2021) conducted a review in Cardiovascular disease and cancer. Cardiovascular disease was evaluated on Cancer risk and outcomes. Cardiovascular disease, developing either before or after a cancer diagnosis, is associated with an increased risk of cancer and worse patient outcomes.