Acute cardiorenal syndrome was associated with a significantly higher risk of death compared with CKD without cardiorenal syndrome (HR 3.13; 95% CI 2.72-3.61; P<0.001).
Cohort (n=30,681)
No
Does the development of different types of cardiorenal syndrome affect mortality and cardiovascular outcomes in patients undergoing echocardiography?
Hazard Ratio: 3.13 (95% CI 2.72–3.61)
p-value: p=<0.001
Background and objectives It is unknown whether echocardiographic parameters are independently associated with the cardiorenal syndrome. No direct comparison of the natural history of various cardiorenal syndrome types has been conducted. Design, setting, participants, 95% confidence interval, 2.72 to 3.61; P <0.001). Patients with cardiorenal type 4 had better survival than patients with acute cardiorenal syndrome (hazard ratio, 0.48; 95% confidence interval, 0.37 to 0.61; P <0.001). Patients with acute cardiorenal syndrome and type 4 had increased risk of myocardial infarction and stroke compared with patients with CKD without cardiorenal syndrome. Conclusions Up to 19% of patients with a chronic form of cardiorenal syndrome will subsequently develop an acute syndrome. Development of acute or type 4 cardiorenal syndrome is independently associated with mortality, the acute form having the worst prognosis.
Mavrakanas et al. (Fri,) conducted a cohort in Cardiorenal syndromes (n=30,681). Acute cardiorenal syndrome vs. CKD without cardiorenal syndrome was evaluated on All-cause mortality (HR 3.13, 95% CI 2.72 to 3.61, p=<0.001). Acute cardiorenal syndrome was associated with a significantly higher risk of death compared with CKD without cardiorenal syndrome (HR 3.13; 95% CI 2.72-3.61; P<0.001).