Characterisation of the Novel HLA-DRB1*07:173 Allele by Sequencing-Based Typing.

Key Points

• To characterize the novel HLA-DRB1*07:173 allele and its differences from HLA-DRB1*07:01:01:01.
• Used sequencing-based typing to analyze the allele.
• Identified differences in codon 41 in exon 2.
• HLA-DRB1*07:173 has one nucleotide substitution compared to HLA-DRB1*07:01:01:01.
• The substitution occurs specifically in codon 41 of exon 2.