An 8-week pulmonary rehabilitation program significantly improved depression (P<0.01), dyspnea (P<0.01), and health-related quality of life (P<0.01) compared to control in patients with severe COPD.
RCT (n=24)
Does an 8-week comprehensive pulmonary rehabilitation program improve depression, anxiety, dyspnea, and health status in patients with severe COPD?
An 8-week comprehensive pulmonary rehabilitation program significantly improves depression, anxiety, dyspnea, and quality of life in patients with severe COPD.
p-value: p=<0.01
OBJECTIVE: To determine the impact of an 8-wk program of comprehensive pulmonary rehabilitation on depression, anxiety, dyspnea, and health-related quality of life in patients with chronic obstructive pulmonary disease (COPD). DESIGN: We studied 24 patients with severe COPD randomized either to pulmonary rehabilitation (PR), (n = 10; FEV1 30 +/- 9%) or control (C; n = 14; FEV1 34 +/- 11%). The PR program included disease education, energy conservation techniques, relaxation, and exercise including 20-min arm elevation with dumbbells and 20-min leg exercise sessions three times a week for 8 wks. At baseline and after completion of the program, all patients were evaluated using the Beck Depression Inventory, State Trait Anxiety Inventory (STAI), Modified Medical Research Council Scale (MRC), and St. George's Respiratory Questionnaire (SGRQ). RESULTS: After PR, there was a significant improvement in the severity of depression (P < 0.01), a decrease in symptoms (P < 0.05), an increase in daily living activities (P < 0.05), and a decrease in the total score of the SGRO (P < 0.01). Dyspnea measured by the MRC scale was significantly better in the PR group (P < 0.01). CONCLUSIONS: The present study shows that in patients with severe COPD, pulmonary rehabilitation induces important changes on depression and anxiety independent of changes in dyspnea and health-related quality-of-life.
Paz-Díaz et al. (Wed,) conducted a rct in Severe chronic obstructive pulmonary disease (COPD) (n=24). Pulmonary rehabilitation vs. Control was evaluated on Severity of depression, symptoms, daily living activities, total SGRQ score, and dyspnea (p=<0.01). An 8-week pulmonary rehabilitation program significantly improved depression (P<0.01), dyspnea (P<0.01), and health-related quality of life (P<0.01) compared to control in patients with severe COPD.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: