Supplementary figure S2 from Tumor Cell–Intrinsic Decr2 Regulates Ferroptosis and Immunotherapy Efficacy
Key Points
Decr2 knockdown in OCI-Ly8 tumor cells led to resistance against CD19-CAR T cell killing in vitro.
B16.SIY tumors with Decr2 knockdown demonstrated resistance to anti-PD-L1 therapy in vivo.
The research highlights the importance of Decr2 in regulating ferroptosis related to tumor response.
Understanding the role of Decr2 may help improve immunotherapy strategies against cancers.
Abstract
Supplementary Figure S2. Decr2 knockdown OCI-Ly8 tumor cells were resistant to CD19-CAR T cell killing in vitro and Decr2 knockdown B16.SIY tumors exhibit resistance to anti-PD-L1 therapy in vivo.
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Supplementary figure S2 from Tumor Cell–Intrinsic Decr2 Regulates Ferroptosis and Immunotherapy Efficacy | Synapse