What type of study is this?

This is a Quantitative Study study (also classified as: Experimental Study).

September 17, 2025

Fast Gradient Ascent Pulse Engineering for parallel transmission pulse design in the small and large tip angle regimes

Key Points

FastGRAPE offers flip angle accuracy comparable to GRAPE and computation time similar to kT-points, enhancing pulse design efficiency.
For short STA excitation, fastGRAPE provides performance on par with GRAPE, outperforming kT-points in pulse optimization.
The approach utilizes Bloch simulation and in vivo acquisitions, applying methods on both commercial and custom pTX RF coils.
FastGRAPE presents a promising strategy for dynamic RF shimming, optimizing balance between accuracy and speed.

Abstract

Motivation: Dynamic RF shimming in pTX at UHF faces two limitations: lengthy computational time of the GRAPE method or lack of precision of parametric approaches (e.g. kT-points). Goal(s): To validate an alternative pulse parameterization, fastGRAPE, potentially offering a better trade-off between the performance and computational speed. Approach: We compare GRAPE, fastGRAPE, and kT-point online and offline pulse designs for a commercial and a custom pTX RF coils at 7T using Bloch simulation and in vivo acquisitions. Results: For short STA excitation, fastGRAPE yields comparable performances to GRAPE and outperforms kT-points. For inversion with the custom coil, online fastGRAPE provides the best flip angle accuracy. Impact: With a flip angle accuracy comparable to GRAPE and a computation time comparable to kT-points, fastGRAPE presents a promising strategy both for online and offline dynamic RF shimming.

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