Supplementary Figure S7 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

Key Points

• A distinct scar-like transcriptomic profile is associated with favorable prognosis in bladder cancer after neoadjuvant therapy.
• The study found significant variations in tumor purity scores across different bladder cancer subtypes, especially between LumP and Scar-like profiles.
• Analysis involved evaluating the ABACUS cohort to categorize tumors into multiple subtypes based on transcriptomic characteristics.
• Identifying these profiles may provide insights into treatment outcomes and guide therapeutic strategies in bladder cancer.