Electrochemical C(sp2)-H Deuterodifluoromethylation of Quinoxalinones and 2H-Indazoles with CF2DSO2Na

Key Points

• The study aims to efficiently introduce the deuterodifluoromethyl group into specific drug molecules.
• Utilized electrochemical methods for the reaction
• Focused on quinoxalinones and 2H-indazoles
• Applied CF2DSO2Na as a reagent
• Successfully achieved deuterodifluoromethylation of targeted compounds
• Demonstrated the process's efficiency in a green chemistry context
• Highlighted improved convenience for drug development