Synthesis of thieno2,3-bindoles by Cloke–Wilson rearrangement of spiro donor–acceptor cyclopropanes

Key Points

• To develop an efficient one-pot synthesis of thieno[2,3-b]indoles using spiro donor–acceptor cyclopropanes.
• Utilized Lawesson’s reagent for thiocarbonyl Cloke–Wilson rearrangement
• Applied oxidative aromatization under open-air conditions
• Employed spiro donor–acceptor cyclopropyl oxindoles as starting materials
• Thieno[2,3-b]indoles were synthesized successfully
• The reaction proceeded smoothly, indicating a robust method
• Produced compounds showed expected structural properties