Validation of Plasma Free Hemoglobin Testing for Extracorporeal Membrane Oxygenation (ECMO) Patients.

Key Points

• The aim is to validate the accuracy and sensitivity of plasma free hemoglobin measurement in ECMO patients.
• Used a direct spectrophotometric method for PFH measurement
• Compared precision and sensitivity against the H-index
• Assessed susceptibility to lipemia affecting measurement
• PFH measurement demonstrated greater precision and sensitivity than the H-index
• Measurement accuracy may decline in cases of lipemia
• Optimal results achieved using high-end spectrophotometers