What question did this study set out to answer?

The aim is to validate the accuracy and sensitivity of plasma free hemoglobin measurement in ECMO patients.

January 25, 20260 citations

Validation of Plasma Free Hemoglobin Testing for Extracorporeal Membrane Oxygenation (ECMO) Patients.

MAMeshach Asare-WereheneUniversity of Ottawa MBMary Kathryn BohnUniversity of New Brunswick BWBianca WanUniversity Health Network

Key Points

The aim is to validate the accuracy and sensitivity of plasma free hemoglobin measurement in ECMO patients.
Used a direct spectrophotometric method for PFH measurement
Compared precision and sensitivity against the H-index
Assessed susceptibility to lipemia affecting measurement
PFH measurement demonstrated greater precision and sensitivity than the H-index
Measurement accuracy may decline in cases of lipemia
Optimal results achieved using high-end spectrophotometers

Abstract

PFH measurement by a direct spectrophotometric method is more precise and sensitive compared to the H-index; however, PFH measurement is susceptible to lipemia unless performed on a high-end spectrophotometer.

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