Treatment of desmoplastic small round cell tumor in the seminal vesicle with chemotherapy, surgery, and radiation led to a partial response in the patient.
Multimodality treatment including chemotherapy, surgery, and radiation therapy can yield a good short-term response in rare cases of DSRCT of the seminal vesicle.
Absolute Event Rate: 0% vs 0%
Desmoplastic small round cell tumor (DSRCT) is an aggressive, uncommon disease and difficult to diagnose and identified by translocation t(11;22) (p13;q12) leading to fusion transcript EWSR1–WT1 . A case of DSRCT of the seminal vesicle diagnosed by histopathology, immunohistochemistry, and genetic study, and treated with chemotherapy, surgery, and radiation therapy on the lines of Ewing Sarcoma protocol is presented. Four cycles of chemotherapy was given, and he had a partial response, so underwent debulking surgery followed by radiation therapy.
Rastogi et al. (Fri,) reported a other. Treatment of desmoplastic small round cell tumor in the seminal vesicle with chemotherapy, surgery, and radiation led to a partial response in the patient.