What question did this study set out to answer?

To explore the association between Leser–Trélat sign and prostate adenocarcinoma.

February 2, 2026

The Sign of Leser–Trélat as a Possible Indicator of Prostate Adenocarcinoma: A Case Report

Key Points

To explore the association between Leser–Trélat sign and prostate adenocarcinoma.
Case presentation of a 65-year-old male with Leser–Trélat sign
Assessment of skin lesions and medical history
Focus on prostate cancer diagnosis in relation to skin symptoms
Patient exhibited sudden onset of multiple seborrhoeic keratoses
Prostate adenocarcinoma diagnosed following skin evaluation
Highlights need for prostate assessment in men with SLT

Abstract

ABSTRACT Backgrounds The sign of Leser–Trélat (SLT) is defined by the abrupt onset of multiple pruritic or nonpruritic seborrhoeic keratoses (SKs) over a short interval, predominantly affecting the back, and is most frequently associated with internal malignant neoplasia, particularly gastric and colorectal adenocarcinoma. Case Presentation We report a rare case of a 65‐year‐old male with SLT in association with prostate adenocarcinoma. Conclusions This report underscores the importance of including prostate assessment in the diagnostic work‐up of men with rapidly evolving, multiple, and progressive SKs.

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The Sign of Leser–Trélat as a Possible Indicator of Prostate Adenocarcinoma: A Case Report

Key Points

Abstract

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