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Case report reveals prostate adenocarcinoma in a man with rapid onset of seborrhoeic keratoses, suggesting diagnostic relevance.
Backgrounds The sign of Leser–Trélat (SLT) is defined by the abrupt onset of multiple pruritic or nonpruritic seborrhoeic keratoses (SKs) over a short interval, predominantly affecting the back, and is most frequently associated with internal malignant neoplasia, particularly gastric and colorectal adenocarcinoma. Case Presentation We report a rare case of a 65‐year‐old male with SLT in association with prostate adenocarcinoma. Conclusions This report underscores the importance of including prostate assessment in the diagnostic work‐up of men with rapidly evolving, multiple, and progressive SKs.
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Hristo Dobrev (2026) studied this question.
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