What question did this study set out to answer?

To analyze the patterns of methadone use during orthopedic surgeries and its effects on pain management.

February 28, 2026

Analysis of perioperative methadone use in patients undergoing orthopedic procedures in the USA: a research report

Key Points

To analyze the patterns of methadone use during orthopedic surgeries and its effects on pain management.
Examined methadone utilization across various US hospitals during orthopedic procedures.
Analyzed comparisons of pain management outcomes in relation to methadone administration.
Assessed opioid requirement reductions post-surgery with methadone use.
Methadone use in orthopedic surgeries is currently uncommon across hospitals.
Variability in usage patterns suggests a lack of standard guidelines.
Patients receiving methadone showed reduced overall opioid consumption postoperatively.

Abstract

Perioperative methadone, a long-acting opioid, may provide durable analgesia and reduce opioid requirements in high-pain orthopedic surgery (spinal fusion, total hip/knee arthroplasty, THA/TKA), yet use remains uncommon and highly variable across US hospitals.11 We examined patterns of

Analysis of perioperative methadone use in patients undergoing orthopedic procedures in the USA: a research report

Key Points

Abstract

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