Analysis reveals varied perioperative methadone use impacting pain management in orthopedic patients, suggesting the need for standardization.
Perioperative methadone, a long-acting opioid, may provide durable analgesia and reduce opioid requirements in high-pain orthopedic surgery (spinal fusion, total hip/knee arthroplasty, THA/TKA), yet use remains uncommon and highly variable across US hospitals.[1][1] We examined patterns of
No takes yet. Share an insight, caveat, or question.
Reisinger et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: