Key result
Perioperative methadone in pediatric patients may decrease postoperative pain, opioid consumption, and length-of-stay, though optimal procedure-specific protocols remain to be established.
Why the study?
Literature evaluating perioperative methadone in children and adolescents is limited, and the superiority of various perioperative protocols has not been established.
Does perioperative methadone improve postoperative pain control and reduce opioid consumption in children and adolescents?
Does perioperative methadone improve postoperative pain control and reduce opioid consumption in children and adolescents?
Perioperative methadone is a promising analgesic for pediatric surgery, but further research is needed to establish optimal procedure-specific protocols and confirm safety and efficacy.
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May inform individualized pediatric perioperative analgesia; leaves open optimal protocols and safety confirmation in prospective trials.
Boisvert‐Plante et al. (2022) conducted a review in Postoperative pain in children and adolescents. Perioperative methadone was evaluated. Perioperative methadone in pediatric patients may decrease postoperative pain, opioid consumption, and length-of-stay, though optimal procedure-specific protocols remain to be established.
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