Bullous pemphigoid (BP) is the most common autoimmune blistering disease in the elderly. Although usually spontaneous, it may be triggered by skin trauma. We report the case of a 90-year-old woman who developed localized BP along a surgical scar one month after orthopedic surgery. Lesions later spread to the trunk. Histology revealed a subepidermal blister with eosinophils, and immunofluorescence confirmed C3 deposition in addition to circulating anti-BP180 antibodies. Clinical improvement was observed following the initiation of topical corticosteroid therapy.
Ouahab et al. (Fri,) studied this question.