Longitudinal analysis of viral suppression before, during, and after pregnancy among women on antiretroviral therapy in Uganda: six-year real-world experience.

Key Points

• The aim is to analyze the effectiveness of antiretroviral therapy on viral suppression during different maternal timelines.
• Conducted a longitudinal analysis over six years.
• Evaluated viral suppression rates before, during, and after pregnancy.
• Compared suppression rates across different ART regimens.
• Assessed adherence levels and their impact on outcomes.
• Viral suppression showed varying effectiveness before and after pregnancy, but not during.
• EFV- and NVP-based regimens achieved comparable suppression rates to DTG.
• PI-based regimens had different outcomes.
• Good adherence was critical for optimal maternal health outcomes.