March 3, 2026Open Access

Safety of secondary CRS/HIPEC in peritoneal surface malignancies: Insights from a national cohort study

Key Points

Secondary CRS/HIPEC shows comparable outcomes to primary CRS/HIPEC in peritoneal surface malignancies.
Reoperation rates and 30-day mortality rates were similar for both secondary and primary CRS/HIPEC.
Adjustment for confounding factors maintained the safety profile of secondary CRS/HIPEC.
Study highlights the feasibility of secondary intervention in selected patients with peritoneal surface malignancies.

Abstract

Secondary CRS/HIPEC can be performed safely in selected patients with PSMs, comparable to primary CRS/HIPEC. Reoperation rates and 30-day mortality rates were similar between groups, even after adjusting for confounding factors.

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Cite This Study

Pollmann et al. (Sat,) studied this question.

synapsesocial.com/papers/69a759edc6e9836116a1f53b https://doi.org/https://doi.org/10.1016/j.ejso.2026.111408

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