Comparison of Lidocaine and Dexmedetomidine in Preventing Fentanyl-induced Cough in Patients Undergoing Elective Surgery: A Blinded Randomized Controlled Trial

Key Points

• Preventing fentanyl-induced cough is equally effective with 0.5 μg × kg-1 of dexmedetomidine and 1.5 mg × kg-1 of lidocaine.
• Hemodynamic parameters exhibit more suppression in the dexmedetomidine group compared to the lidocaine group.
• This is a blinded randomized controlled trial comparing lidocaine and dexmedetomidine for cough prevention.
• Implication highlights the need for careful dosage selection to avoid excessive hemodynamic changes.