Blinded randomized controlled trial shows lidocaine and dexmedetomidine equally prevent cough in surgery, indicating dosage balance needed for patient safety.
The results of this study demonstrated that 0.5 μg × kg⁻¹ of DEX and 1.5 mg × kg⁻¹ of LIDO are equally effective in preventing FIC. However, hemodynamic parameters are more markedly suppressed in the DEX group compared to the lidocaine group.
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Jarineshin et al. (2026) studied this question.
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