March 3, 2026Open Access

Prenatal PFAS exposure and childhood respiratory allergic diseases: Findings from Shanghai Birth cohort Consortium

Key Points

Children exposed to prenatal PFAS exhibit higher rates of respiratory allergic diseases, particularly allergic rhinitis.
Among those, children born to mothers with elevated PM2.5 levels face increased susceptibility to these conditions.
The analysis involved data from the Shanghai Birth cohort Consortium assessing environmental exposure impact.
Reducing exposures to prenatal PFAS and PM2.5 may have significant public health benefits for minimizing childhood respiratory issues.

Abstract

Prenatal exposure to individual and PFAS mixture was associated with an increased risk of childhood RAD, particularly allergic rhinitis. Children born to mothers with high PM2. 5 levels during pregnancy were more susceptible. Reducing prenatal PFAS and PM2.5 exposure may reduce the public health burden of childhood RAD.

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Cite This Study

Hu et al. (Sun,) studied this question.

synapsesocial.com/papers/69a76563badf0bb9e87d8e9b https://doi.org/https://doi.org/10.1016/j.envint.2026.110118

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