Prenatal PFAS exposure and childhood respiratory allergic diseases: Findings from Shanghai Birth cohort Consortium

Yabin Hu; Qian Chen; Jianya Xi; Yingya Zhao; Liyi Zhang; Yuyan Gui; Wei Yuan; Maohua Miao; Yu Gao; Ying Tian; Huijing Shi; Hong Liang; Jun Zhang; Yunhui Zhang

doi:10.1016/j.envint.2026.110118

February 1, 2026Environment InternationalOpen Access

Prenatal PFAS exposure and childhood respiratory allergic diseases: Findings from Shanghai Birth cohort Consortium

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Key Points

Children exposed to prenatal PFAS exhibit higher rates of respiratory allergic diseases, particularly allergic rhinitis.
Among those, children born to mothers with elevated PM2.5 levels face increased susceptibility to these conditions.
The analysis involved data from the Shanghai Birth cohort Consortium assessing environmental exposure impact.
Reducing exposures to prenatal PFAS and PM2.5 may have significant public health benefits for minimizing childhood respiratory issues.

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Implication

Observational analysis shows increased childhood allergic rhinitis risk in children exposed to PFAS during pregnancy, suggesting harm reduction potential.

Abstract

Prenatal exposure to individual and PFAS mixture was associated with an increased risk of childhood RAD, particularly allergic rhinitis. Children born to mothers with high PM₂. ₅ levels during pregnancy were more susceptible. Reducing prenatal PFAS and PM2.5 exposure may reduce the public health burden of childhood RAD.

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Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/69a76563badf0bb9e87d8e9b https://doi.org/10.1016/j.envint.2026.110118

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Prenatal PFAS exposure and childhood respiratory allergic diseases: Findings from Shanghai Birth cohort Consortium

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Prenatal PFAS exposure and childhood respiratory allergic diseases: Findings from Shanghai Birth cohort Consortium

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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