Evaluation of the effects of silver nanoparticles and ciprofloxacin on apoptotic gene expression (BAX, Bcl-2, and caspase-3) in NALM-6 acute lymphoblastic leukemia progenitor B cells | Synapse
March 3, 2026
Evaluation of the effects of silver nanoparticles and ciprofloxacin on apoptotic gene expression (BAX, Bcl-2, and caspase-3) in NALM-6 acute lymphoblastic leukemia progenitor B cells
Key Points
Increased expression of BAX and caspase-3, suggesting enhanced apoptosis in NALM-6 cells.
Ciprofloxacin combined with silver nanoparticles led to significant changes in gene regulation.
Analysis employed quantitative PCR to measure gene expression levels in leukemia cells,
Study supports potential dual therapy advantages using nanoparticles and antibiotics in cancer treatment.