Evaluation of the effects of silver nanoparticles and ciprofloxacin on apoptotic gene expression (BAX, Bcl-2, and caspase-3) in NALM-6 acute lymphoblastic leukemia progenitor B cells

Key Points

• Increased expression of BAX and caspase-3, suggesting enhanced apoptosis in NALM-6 cells.
• Ciprofloxacin combined with silver nanoparticles led to significant changes in gene regulation.
• Analysis employed quantitative PCR to measure gene expression levels in leukemia cells,
• Study supports potential dual therapy advantages using nanoparticles and antibiotics in cancer treatment.