What question did this study set out to answer?

The aim is to review methods for measuring adherence to oral anticancer medications in African women during therapy initiation, implementation, and discontinuation.

March 4, 2026Open Access

A Systematic Review of Methods to Measure Adherence to Oral Anticancer Medications in African Women With Breast Cancer at Initiation, Implementation, and Discontinuation of Therapy.

Key Points

The aim is to review methods for measuring adherence to oral anticancer medications in African women during therapy initiation, implementation, and discontinuation.
Conducted a systematic review of adherence measurement methods
Focused on different phases: initiation, implementation, and discontinuation
Evaluated the reliability and validity of self-report measures
Implementation phase was the most assessed, while initiation and discontinuation phases were less studied
Self-report measures were commonly used but lacked reliability and validity
Recommendations highlight the need for better psychometric evaluation of adherence measures

Abstract

The implementation phase was the most commonly assessed. Initiation and discontinuation phases were relatively less assessed. Self-report measures were the most frequently used, but the reliability and validity of these measures are lacking, hence limiting the evidence to guide practice. Thus, measures with sound psychometric properties, including reliability and validity, that can assess OAM adherence across its three phases are needed to improve adherence measurement and patient outcomes, particularly in Africa.

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