Nanopore Sequencing of Previously Unreported HLA ‐ DRA Alleles

Key Points

• To identify new HLA-DRA alleles among a large population during donor typing for hematopoietic stem cell transplantation.
• Conducted donor typing for HSCT in a cohort of 8,000 individuals.
• Utilized nanopore sequencing technology to analyze HLA-DRA alleles.
• Detected sixteen novel HLA-DRA alleles among the individuals typed.
• Extended the understanding of genetic diversity in HLA-DRA relevant to HSCT.