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March 24, 2026HLA

Nanopore Sequencing of Previously Unreported HLA ‐ DRA Alleles

Althea Malik Yannik Busch Claudia Lehmann Marco Schäfer Wolfgang Peter

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Key Points

To identify new HLA-DRA alleles among a large population during donor typing for hematopoietic stem cell transplantation.
Conducted donor typing for HSCT in a cohort of 8,000 individuals.
Utilized nanopore sequencing technology to analyze HLA-DRA alleles.
Detected sixteen novel HLA-DRA alleles among the individuals typed.
Extended the understanding of genetic diversity in HLA-DRA relevant to HSCT.

Implication

Novel alleles of HLA-DRA were identified in a routine donor typing for HSCT, implying potential implications for transplantation.

Abstract

Sixteen novel HLA‐DRA alleles were detected among 8,000 individuals during routine donor typing for HSCT.

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Cite This Study

Malik et al. (2026) studied this question.

synapsesocial.com/papers/69c4cd25fdc3bde44891916c https://doi.org/10.1111/tan.70684

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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