Dual Beneficial Effects of Topical l ‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice

Key Points

• This research aims to explore the effects of topical l-glutamine on oral mucositis in mice treated with 5-fluorouracil.
• Topical application of l-glutamine was used
• Mice were treated with 5-fluorouracil to induce oral mucositis
• Inflammation and tissue remodeling were assessed
• L-glutamine reduced inflammation related to oral mucositis
• Improved tissue remodeling was observed in treated mice
• The treatment showed a dual beneficial effect on mucositis symptoms