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August 16, 2002Advanced Materials107 citationsOpen Access

Gel Machines Constructed from Chemically Cross-linked Actins and Myosins

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AKAkira KakugoSSShin-ichiro SugimotoJGJian Ping Gong

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Abstract

An ATP-fueled soft gel machine reconstructed from polymer-crosslinked actin muscle protein (“giant-actin”) and analogously modified myosin has been built by Osada and co-workers. The “giant-actin” gel filaments (several 1000 times larger by volume than native actin, see Figure) move along their myosin counterparts as fast as native F-actin. Such machines should work inside their body of origin without eliciting immunoreactions.

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Kakugo et al. (2002) studied this question.

synapsesocial.com/papers/69dac2d74e9a02dbaa6846f0https://doi.org/10.1002/1521-4095(20020816)14:16<1124::aid-adma1124>3.0.co;2-m
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