July 12, 2011Open Access

Decreased brain stiffness in Alzheimer's disease determined by magnetic resonance elastography

Does 3D magnetic resonance elastography detect changes in brain tissue stiffness in patients with Alzheimer's disease?

Population

Patients with Alzheimer's disease (AD)

Intervention

3D magnetic resonance elastography (MRE) of the brain

Outcome

Brain tissue stiffnesssurrogate

3D MRE is a reproducible imaging technique that detects significantly reduced brain tissue stiffness in Alzheimer's disease.

3D MRE of the brain can be performed reproducibly and demonstrates significantly reduced brain tissue stiffness in patients with AD.

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