Why the study?
Does 3D magnetic resonance elastography detect changes in brain tissue stiffness in patients with Alzheimer's disease?
Does 3D magnetic resonance elastography detect changes in brain tissue stiffness in patients with Alzheimer's disease?
3D MRE is a reproducible imaging technique that detects significantly reduced brain tissue stiffness in Alzheimer's disease.
Supports 3D MRE as an AD research biomarker; leaves open clinical diagnostic use pending validation.
3D MRE of the brain can be performed reproducibly and demonstrates significantly reduced brain tissue stiffness in patients with AD.
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Murphy et al. (2011) studied this question.
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