Predictors of treatment failure in children living with HIV starting first-line antiretroviral therapy in the ODYSSEY trial

Key Points

• The research aims to identify factors predicting treatment failure in children with HIV starting first-line therapy.
• Analyzed data from the ODYSSEY trial
• Focused on children beginning antiretroviral therapy
• Evaluated age, BMI-for-age, and CD4% at treatment initiation
• Young age is linked to higher treatment failure risk
• Low BMI-for-age is associated with treatment challenges
• Low CD4% at ART initiation points to increased failure instances