Inducing and monitoring photothrombotic stroke in anesthetic neuroprotection-free mice using functional photoacoustic microscopy

Key Points

• The research aims to establish a method for inducing and monitoring microvascular changes during cerebral ischemia without anesthesia.
• Inducing photothrombotic stroke in mice without anesthetics
• Using functional photoacoustic microscopy for monitoring
• Analyzing vascular changes in real-time
• Successfully induced cerebral ischemia in anesthetic-free mice
• Demonstrated precise monitoring of vascular changes
• Established a reliable microvascular-level analysis tool